Profile

PGI / Departmental Research Projects

PGI / Departmental Research Projects

1978

  • Pyogenic meningitis - A retrospective analysis from 1970-1976.

1982

  • Non compressive myelopathy - A prospective study.
  • Continuous muscle fibre activity - A clinical, electrophysiological and biochemical study.

1983

  • Stroke in Young - Immunological studies and electron microscope studies of platelets.
  • Polymyositis - A Clinical, electrophysiological and histopathological study of 25 cases.
  • Clinical, electrophysiological, immunological and biological studies in post-conjunctivitis neurologic complications.
  • Myasthenia Gravis - A clinical and electrophysiological study.

1984

  • Clinical, electrophysiological and radiological study of wasted hand syndrome.

1985

  • Pattern of motor neurone disease in North India.
  • Pattern of spinocerebellar degeneration in North India.

1986

  • Clinical profile of non inflammatory primary muscle diseases.

1987

  • Brain stem and visual evoked responses in spinocerebellar degeneration.

1988

  • Biochemical and electrophysiological studies in motor neurone disease.
  • Study of extracranial criteria in stroke using Doppler arterial scan.
  • Efficacy of cysticidal drugs (Praziquantel and Albendozole) in treatment of neurocysticercosis.
  • Vanishing radiological lesions in epilepsy.

1989

  • Primary sensory neurone abnormality and serum Vitamin E in spinocerebellar degeneration.

1993

  • Intravenous Lignocaine for status epilepticus.

1994

  • Glucocorticoids in adults pyogenic meningitis. A randomised prospective trial.
  • Auditory function after lumbar puncture.
  • Efficacy of neuromapping in partial seizures.
  • E.E.G., brain mapping, and C.T. in cases of stroke. A comparative study.
  • Clinical and neurophysiological evaluation of scleroderma patients having CNS involvement and psychiatric manifestations.

1995

  • Cerebrovascular complications in Pyogenic meningitis in adult. A clinical and radiological study.
  • Immunological profile : single small enhancing CT lesions vs neurocysticercosis.
  • Electrophysiological, vascular and psychometric studies in migraine.

1996

  • Idebenon Clinical Trial in cases of cerebrovascular disorders. - Co-Investigator
  • Incidence of HTLV-1 antibodies in patients with non-compressive myelopathy
  • Clinical and electrophysiological evaluation of myoclonic epilepsy in India.

1997

  • Seizure in acute strokes. Management Strategy.
  • Treatment seeking behavior and psychosocial dysfunctioning in adult epileptics.
  • Clinical and electrophysiological evaluation of peripheral nerves in Thyrotoxicosis.
  • Central nervous system complications during induction therapy of childhood lymphoreticular malignancy.
  • Clinical and electrophysiological aspects of neuromuscular changes, before and after induction therapy of childhood lymphoreticular malignancy.

1998

  • Parkinson's disease – A study of changes P-300 potential in relation to therapy and cognition.
  • Non haemorrhagic stroke : Predicting prognosis by transcranial magnetic stimulation.

1999

  • Oligoclonal bands in Multiple sclerosis
  • Study of complicated Migraine.

2001

  • Transcranial and Cervical Magnetic Stimulation in Amyotrophic Lateral Sclerosis and Cervical Myelopathy.
  • Auditory Event related P-300 potentials and peripheral nerve conduction studies in Liver cirrhosis.

2003

  • Effect of Sodium Valproate as prophylactic agent in migraine.
  • INH induced peripheral neuropathy – electrophysiological study.

2004

  • Small single enhancing CT lesion (SSECTL): Alteration in cognition P300 and transcranial magnetic stimulation (TCMS).
  • Identification and characterisation of differentially expressed gene transcripts in DMD/BMD patients

2005

  • Cognition and cerebral perfusion SPECT in Parkinson's disease
  • The clinical spectrum of afferent visual pathway defects in Migraine.

2006

  • A comparative study of Bell's palsy treatment with acyclovir and prednisolone compared with prednisolone alone : A randomized blinded clinical and electrophysiological study
  • Spectrum of peripheral neuropathy in Rheumatoid Arthritis.

2007

  • Multifocal Dystonias – Aetiopathological factors
  • Writer's Cramp – Clinical variants and response to Botulinum toxin
  • Clinical Profile and demography of Dystonias
  • Confirmation of seizure semiology by Video EEG
  • Evaluation of Epilepsy related physical injuries
  • The contribution of carotid atherosclerosis disease in young stroke patients with a Prothrombotic State
  • A comparative study of Bell's palsy treatment with acyclovir and prednisolone compared with prednisolone alone : A randomized blinded clinical and electrophysiological study
  • Spectrum of peripheral neuropathy in Rheumatoid Arthritis.

2009

  • Establishment of NMDA induced retinal injury mouse model.
  • Role of VEGF on the ciliary epithelial cell proliferation and its effect on the expression of Notch, Jagged, β catenin, SSEA1 and N Cadherin.
  • Assessment of bone marrow derived Lin- Sca-1+ stem cell implantation in experimentally induced stroke related retinal ischemia mouse model.
  • The effect of human umbilical cord blood derived Lineage negative stem cells in reversal of amyloid β peptide induced memory loss in mice.
  • Role of autologous bone marrow derived stem cell therapy in management of patients with motor neuron disease : A Pilot Study
  • Role of autologous bone marrow derived Stem cell therapy in management of patients with Motor Neuron Disease : A pilot study.
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